Non-invasive neuromodulation

Breaking the barrier
to the brain.

Focused ultrasound. Smartphone guidance.
A new approach to neuromodulation, in development.

Conceptual illustration of the brain formed from fine fibres, with a red focal region
01 / The possibility of precisionConceptual illustration
Research in progress

DeepBrain is developing a non-invasive focused-ultrasound headset and smartphone companion for future clinician-supervised use. It is not available to buy. Clinical performance figures are design targets pending clinical confirmation.

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Research and advisory network
University of Nottingham University of Strathclyde University of Cambridge

01 / The access challenge

Making brain stimulation more accessible.

Implanted deep brain stimulation already exists and requires surgery. Different stimulation approaches have different targeting and supervision requirements. DeepBrain is exploring a non-invasive approach intended for future clinician-supervised use.

01

Non-invasive access. Explore brain stimulation without an implanted device.

02

Targeting precision. Evaluate the accuracy of smartphone-guided placement and focused ultrasound.

03

Clinical evidence. Establish safety and outcomes before any proposed treatment use.

02 / The science of precision

Precision targeting in development,
guided by a phone.

The proposed system combines focused ultrasound with smartphone-guided placement. The intended closed loop would use biosignals to inform dose adjustments. Targeting accuracy, safety and clinical outcomes need evaluation.

Conceptual translucent head showing neural fibres and acoustic paths converging on a deep brain region
Precision, beneath the surface01 — 03
01 / Placement guided by your phoneConceptual artwork · Not a clinical scan

Three connected design questions: where to place, where to focus and how to adapt.

  1. 01

    Precise placement

    The proposed phone guidance would support headset placement. Accurate targeting without MRI is a design aim that needs validation.

  2. 02

    Reach the right target

    The design explores targeting deeper regions such as the thalamus and amygdala. The atlas illustrates that intent, rather than proven device performance.

  3. 03

    Adapt with AI

    The intended closed loop would use EEG and HRV to inform dose adjustments. Its performance and clinical value need evaluation.

The interactive atlas

Explore what
lies beneath.

Explore three target regions in the brain. Rotate the model, choose a target and see how the illustrative focal depth changes.

An interactive explanation of the design intent. This is not a treatment simulator or a clinical scan.

Select a region to explore
Target · ThalamusInteractive anatomy
1.0×

Drag to rotate. Use the controls to zoom or reset.

Focal depth
~55 mm
Focal energy
0.46 W/cm²
Approach
Non-invasive
Mode
Closed loop
Stimulation intensity 55% · Moderate

Compare the illustrative focal response. These are not treatment settings.

Design targets, dose-limited. Pending clinical confirmation.

The companion experience

From placement
to perspective.

A proposed companion for each stage of a session. Guidance on your phone, with your clinician in the loop.

Conceptual ivory anatomical sculpture showing a deep brain focal region
Conceptual anatomy · Not a clinical scan

Placement

A clear starting point.

The phone is designed to guide headset placement, helping bring the focal point towards the intended target.

AligningIllustration
Horizontal+4.2 mm
Vertical−2.8 mm
Tilt1.6°

The values illustrate the interface. They are not measurements from a connected headset.

Companion concept · In development. No medical advice or live device connection.

04 Comparison

Three ambitions.
One approach.

Deep targeting. Use beyond the clinic. Adaptation to the individual. DeepBrain is designed to bring them together.

DeepBrain’s design intent

Bring precision
closer to daily life.

Each approach makes different trade-offs. Our aim is to combine deep targeting with non-invasive use and personalisation.

01

Implants

Deep access, with an invasive procedure.

02

Clinic systems

Targeted stimulation in a clinical setting.

03

Consumer wearables

Convenience at home, with limits on deep targeting.

Compare the five capabilities
Capability comparison between implants, clinic systems, consumer wearables and DeepBrain.
Capability Implants Clinic systems Consumer wearables DeepBrain
Non-invasive NoYesYesYes
Reaches deeper targets YesYesNoYes
Designed for home use NoNoYesYes
No MRI required n/aNoYesYes
AI personalisation LimitedLimitedNoYes

Comparison reflects DeepBrain’s design intent versus typical alternatives. All performance figures are design targets pending clinical confirmation.

05 Safety

Safety is part of the design.

Home use has to be safe by default, so these controls are part of the design from the start.

  • DOSE

    Dose ceilings

    The design proposes limits on intensity and duration. Appropriate session schedules and dose limits need clinical evaluation.

  • SIGNAL

    Live monitoring

    The intended monitoring system would flag readings outside expected ranges. Its reliability and response rules need testing.

  • OVERSIGHT

    Clinician oversight

    Future home use would require appropriate clinical supervision and a tested monitoring workflow.

  • ACCESS

    Secure by default

    Device integrity and access controls are development requirements. Security controls need evaluation before deployment.

Conceptual neural fibres crossing a dark field with one red thread
The next chapter is clinical evidence.Conceptual illustration

06 Roadmap

From the lab to the living room.

Current work

Prototype evaluation

Prototype development and planned feasibility studies. Published clinical outcome evidence for the proposed device is not available on this site.

Next evidence milestone

Clinical pilot

Structured clinician interviews and a clinical pilot, with safety, monitoring and the regulatory pathway toward UKCA and CE marking.

Longer-term ambition

Supervised home use

Future ambition: supervised home programmes, subject to clinical evidence, safety evaluation and the applicable regulatory pathway.

07 Team

Who is building DeepBrain.

Neuromodulation, brain-network science, biomedical engineering, AI and commercial execution, in one team.

  • Om Roy
    Om Roy
    CEO · AI and neuromodulation
    University of Strathclyde
  • Prof. Marcus Kaiser
    Prof. Marcus Kaiser
    CSO · Brain networks
    University of Nottingham
  • Dr. Keith Smith
    Dr. Keith Smith
    Biomedical Lead
    University of Strathclyde
  • Dr. Yashar Moshfeghi
    Dr. Yashar Moshfeghi
    AI Lead
    University of Strathclyde
  • Alex Christou
    Alex Christou
    Business Development
    University of Strathclyde
Advisory board
  • Peter SchlechtVenture capital
  • Prof. Feng HaoCambridge · Security engineering
  • Paul CableCEO · NeuPulse
  • Jon HackerCEO · NeurGear
  • Dave HughesCEO · Halya

08 Questions

Common questions.

Is DeepBrain a medical device I can buy today?

No. DeepBrain is a pre-launch development project. The proposed headset and companion app are not available to buy. Clinical effectiveness, safety and regulatory requirements need evaluation before treatment or home use.

How is this different from a consumer wellness wearable?

DeepBrain is exploring focused ultrasound, smartphone-guided placement and adaptive monitoring. The aim is future clinician-supervised use beyond the clinic. These are development goals, not demonstrated advantages over every other device.

Does it require surgery or an MRI?

The proposed approach is non-invasive and aims to use smartphone-guided placement without MRI. These are design goals whose accuracy and safety still need evaluation.

How do you keep home use safe?

The design proposes session limits, dose ceilings, biosignal monitoring and clinician oversight. These safeguards need testing and clinical evaluation. This website does not offer treatment or individual dosing advice.

Who is behind DeepBrain?

A team spanning neuromodulation, brain-network science, biomedical engineering, AI and commercial execution, drawn from the Universities of Nottingham and Strathclyde, with an advisory board across venture capital, security engineering and neurotech.

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